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Zolpidem tartrate.
Description
Each tablet contains zolpidem tartrate 6.25mg or 12.5mg. Zolpidem tartrate is a white to off white colourless, crystalline powder, sparingly soluble in water.
Excipients/Inactive Ingredients: Lactose, microcrystalline cellulose, hypromellose, sodium starch glycollate type A, magnesium stearate, silica colloidal anhydrous, titanium dioxide, macrogol 3350, potassium acid tartrate, iron oxide red CI77491 (STILNOX CR 6.25 mg only), iron oxide yellow CI77492 (STILNOX CR 12.5 mg only) and indigo carmine CI73015 (STILNOX CR 12.5 mg only).
Excipients/Inactive Ingredients: Lactose, microcrystalline cellulose, hypromellose, sodium starch glycollate type A, magnesium stearate, silica colloidal anhydrous, titanium dioxide, macrogol 3350, potassium acid tartrate, iron oxide red CI77491 (STILNOX CR 6.25 mg only), iron oxide yellow CI77492 (STILNOX CR 12.5 mg only) and indigo carmine CI73015 (STILNOX CR 12.5 mg only).
Indications/Uses
STILNOX CR is indicated for the short-term treatment of insomnia in adults (see Dosage & Administration).
Dosage/Direction for Use. Buy Stilnox online, zolpidem for sale in Australia
STILNOX CR acts rapidly and should therefore be taken immediately before retiring, or in bed. STILNOX CR should be taken in a single intake and not be re-administered during the same night. As with all hypnotics, long-term use of zolpidem is not recommended. Treatment should be as short as possible and should not exceed four weeks.
For oral use only.
Discontinuation of treatment: see Adverse Reactions.
Withdrawal Effects: see Precautions.
Recommended Dosage: Tablets should not be divided, crushed or chewed. Buy Stilnox online, zolpidem for sale in Australia
Adults: The recommended daily dose is 12.5 mg. The lowest effective daily dose of zolpidem should be used and not exceed 12.5mg.
Elderly or Debilitated Patients: Elderly or debilitated patients may be especially sensitive to the effects of zolpidem. The recommended daily dose is 6.25 mg.
Hepatic Impairment: As clearance and metabolism of zolpidem is reduced in hepatic impairment, caution should be exercised in these patients with particular caution being exercised in elderly patients. The recommended daily dose is 6.25 mg and these patients should be closely monitored. STILNOX CR should not be used in patients with severe hepatic impairment (see Contraindications).
Renal impairment: No dosage adjustment is necessary in these patients, although they should be closely monitored.
Children: As the safety and efficacy of STILNOX CR has not yet been established, the use of STILNOX CR in children under 18 years of age is contraindicated. Buy Stilnox online, zolpidem for sale in Australia
For oral use only.
Discontinuation of treatment: see Adverse Reactions.
Withdrawal Effects: see Precautions.
Recommended Dosage: Tablets should not be divided, crushed or chewed. Buy Stilnox online, zolpidem for sale in Australia
Adults: The recommended daily dose is 12.5 mg. The lowest effective daily dose of zolpidem should be used and not exceed 12.5mg.
Elderly or Debilitated Patients: Elderly or debilitated patients may be especially sensitive to the effects of zolpidem. The recommended daily dose is 6.25 mg.
Hepatic Impairment: As clearance and metabolism of zolpidem is reduced in hepatic impairment, caution should be exercised in these patients with particular caution being exercised in elderly patients. The recommended daily dose is 6.25 mg and these patients should be closely monitored. STILNOX CR should not be used in patients with severe hepatic impairment (see Contraindications).
Renal impairment: No dosage adjustment is necessary in these patients, although they should be closely monitored.
Children: As the safety and efficacy of STILNOX CR has not yet been established, the use of STILNOX CR in children under 18 years of age is contraindicated. Buy Stilnox online, zolpidem for sale in Australia
Overdosage
Signs and Symptoms: In reports of overdose with immediate-release zolpidem alone or with other CNS depressant agents (including alcohol), impairment of consciousness has ranged from somnolescence to coma, and more severe symptomatology, including fatal outcomes have been reported. Fatalities have occurred when overdoses of multi CNS depressants were taken. No differences were identified with reports of overdose with controlled release zolpidem.
Management: General symptomatic and supportive measures should be used, along with immediate gastric lavage where appropriate. Intravenous fluids should be administered as needed. Sedative drugs should be withheld, even if excitation occurs.
Zolpidem has been shown in trials to be non-dialysable. Buy Stilnox online, zolpidem for sale in Australia
Use of flumazenil may be considered when serious symptoms are observed. However, flumazenil administration may contribute to the appearance of neurological symptoms, such as convulsions, since zolpidem does not exhibit the anticonvulsant effects of benzodiazepines.
Management: General symptomatic and supportive measures should be used, along with immediate gastric lavage where appropriate. Intravenous fluids should be administered as needed. Sedative drugs should be withheld, even if excitation occurs.
Zolpidem has been shown in trials to be non-dialysable. Buy Stilnox online, zolpidem for sale in Australia
Use of flumazenil may be considered when serious symptoms are observed. However, flumazenil administration may contribute to the appearance of neurological symptoms, such as convulsions, since zolpidem does not exhibit the anticonvulsant effects of benzodiazepines.
Contraindications. Buy Stilnox online, zolpidem for sale in Australia
Sleep apnoea; Known hypersensitivity to zolpidem or other ingredients in the tablet; Myasthenia gravis; Severe hepatic insufficiency; Acute and/or severe pulmonary insufficiency; Prior or concomitant intake with alcohol; STILNOX CR should not be prescribed for children under 18 years of age.
Warnings
Zolpidem may be associated with potentially dangerous complex sleep-related behaviours which may include sleep walking, sleep driving and other bizarre behaviours. Zolpidem is not to be taken with alcohol. Caution is needed with other CNS depressant drugs. Limit use to four weeks maximum under close medical supervision.
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