5 mg: Each tablet contains 5 mg tadalafil.
Excipient with known effect: Each coated tablet contains 121 mg lactose (as monohydrate).
20 mg: Each tablet contains 20 mg tadalafil.
Excipient with known effect: Each coated tablet contains 233 mg lactose (as monohydrate).
Excipients/Inactive Ingredients: 5 mg: Tablet core: lactose monohydrate, croscarmellose sodium, hydroxypropylcellulose, microcrystalline cellulose, sodium laurilsulfate, magnesium stearate.
Film-coat: lactose monohydrate, hypormellose, triacetin, titanium dioxide (E171), iron oxide yellow (E172), talc.
20 mg: Tablet core: lactose monohydrate, croscarmellose sodium, hydroxypropylcellulose, microcrystalline cellulose, sodium laurilsulfate, magnesium stearate. Buy Cialis Online, tadalafil for sale in Australia
Film-coat: colour mixture Opadry II Yellow, talc.
Description. Buy Cialis Online, tadalafil for sale in Australia
Action
Pharmacotherapeutic Group: Urologicals, Drugs used in erectile dysfunction. ATC Code: G04BE08.
Pharmacology: Pharmacodynamics: Mechanism of Action: Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum. This results in smooth muscle relaxation and inflow blood into the penile tissues, thereby producing an erection. Tadalafil has no effect in the treatment of erectile dysfunction in the absence of sexual stimulation. Buy Cialis Online, tadalafil for sale in Australia
5 mg: The effect of PDE5 inhibition on cGMP concentration in the corpus cavernosum is also observed in the smooth muscle on the prostate, the bladder and their vascular supply. The resulting vascular relaxation increases blood perfusion which may be the mechanism by which symptoms of benign prostatic hyperplasia are reduced. These vascular effects may be complemented by inhibition of bladder afferent nerve activity and smooth muscle relaxation of the prostate and bladder.
Pharmacology: Pharmacodynamics: Mechanism of Action: Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum. This results in smooth muscle relaxation and inflow blood into the penile tissues, thereby producing an erection. Tadalafil has no effect in the treatment of erectile dysfunction in the absence of sexual stimulation. Buy Cialis Online, tadalafil for sale in Australia
5 mg: The effect of PDE5 inhibition on cGMP concentration in the corpus cavernosum is also observed in the smooth muscle on the prostate, the bladder and their vascular supply. The resulting vascular relaxation increases blood perfusion which may be the mechanism by which symptoms of benign prostatic hyperplasia are reduced. These vascular effects may be complemented by inhibition of bladder afferent nerve activity and smooth muscle relaxation of the prostate and bladder.
Indications/Uses
Treatment of erectile dysfunction in adult males.
In order for tadalafil to be effective for the treatment of erectile dysfunction, sexual stimulation is required.
CIALIS is not indicated for use by women.
5 mg: Treatment of the signs and symptoms of benign prostatic hyperplasia in adult males.
In order for tadalafil to be effective for the treatment of erectile dysfunction, sexual stimulation is required.
CIALIS is not indicated for use by women.
5 mg: Treatment of the signs and symptoms of benign prostatic hyperplasia in adult males.
Dosage/Direction for Use Buy Cialis Online, tadalafil for sale in Australia
Posology: Erectile dysfunction in adult men: In general, the recommended dose is 10 mg taken prior to anticipated sexual activity and with or without food.
In those patients in whom tadalafil 10 mg does not produce an adequate effect, 20 mg might be tried. It may be taken at least 30 minutes prior to sexual activity.
The maximum dose frequency is once per day.
Tadalafil 10 and 20 mg is intended for use prior to anticipated sexual activity and it is not recommended for continuous daily use.
In patients who anticipate a frequent use of CIALIS (i.e., at least twice weekly) a once daily regimen with the lowest doses of CIALIS might be considered suitable, based on patient choice and the physician’s judgement.
In these patients the recommended dose is 5 mg taken once a day at approximately the same time of day. The dose may be decreased to 2.5mg once a day based on individual tolerability. Buy Cialis Online, tadalafil for sale in Australia
The appropriateness of continued use of the daily regimen should be reassessed periodically.
Benign prostatic hyperplasia in adult men: 5 mg: The recommended dose is 5 mg, taken at approximately the same time every day with or without food. For adult men being treatment for both benign prostatic hyperplasia and erectile dysfunction the recommended dose is also 5 mg taken at approximately the same time every day. Patients who are unable to tolerate tadalafil 5 mg for the treatment of benign prostatic hyperplasia should consider an alternative therapy as the efficacy of tadalafil 2.5mg for the treatment of benign prostatic hyperplasia has not been demonstrated.
Special populations: Elderly men: Dose adjustments are not required in elderly patients. Buy Cialis Online, tadalafil for sale in Australia
Men with renal impairment: Dose adjustments are not required in patients with mild to moderate renal impairment. For patients with severe renal impairment 10 mg is the maximum recommended dose for on-demand treatment.
5 mg: Once-a-day dosing of 2.5 or 5 mg tadalafil both for the treatment of erectile dysfunction or benign prostatic hyperplasia is not recommended in patients with severe renal impairment (see Precautions and Pharmacology: Pharmacokinetics under Actions).
20 mg: Once-a-day dosing of tadalafil is not recommended in patients with severe renal impairment (see Precautions and Pharmacology: Pharmacokinetics under Actions). Buy Cialis Online, tadalafil for sale in Australia
Men with hepatic impairment: For the treatment of erectile dysfunction using on-demand CIALIS the recommended dose of CIALIS is 10 mg taken prior to anticipated sexual activity and with or without food. There is limited clinical data on the safety of CIALIS in patients with severe hepatic impairment (Child-Pugh Class C); if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician. There are no available data about the administration of doses higher than 10 mg of tadalafil to patients with hepatic impairment.
Once-a-day dosing of CIALIS both for the treatment of erectile dysfunction and benign prostatic hyperplasia has not been evaluated in patients with hepatic impairment; therefore, if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician. (see Precautions and Pharmacology: Pharmacokinetics under Actions). Buy Cialis Online, tadalafil for sale in Australia
Men with diabetes: Dose adjustments are not required in diabetic patients.
Paediatric population: There is no relevant use of CIALIS in the paediatric population with regard to the treatment of erectile dysfunction.
Method of administration: CIALIS film-coated tablet if for oral use.
In those patients in whom tadalafil 10 mg does not produce an adequate effect, 20 mg might be tried. It may be taken at least 30 minutes prior to sexual activity.
The maximum dose frequency is once per day.
Tadalafil 10 and 20 mg is intended for use prior to anticipated sexual activity and it is not recommended for continuous daily use.
In patients who anticipate a frequent use of CIALIS (i.e., at least twice weekly) a once daily regimen with the lowest doses of CIALIS might be considered suitable, based on patient choice and the physician’s judgement.
In these patients the recommended dose is 5 mg taken once a day at approximately the same time of day. The dose may be decreased to 2.5mg once a day based on individual tolerability. Buy Cialis Online, tadalafil for sale in Australia
The appropriateness of continued use of the daily regimen should be reassessed periodically.
Benign prostatic hyperplasia in adult men: 5 mg: The recommended dose is 5 mg, taken at approximately the same time every day with or without food. For adult men being treatment for both benign prostatic hyperplasia and erectile dysfunction the recommended dose is also 5 mg taken at approximately the same time every day. Patients who are unable to tolerate tadalafil 5 mg for the treatment of benign prostatic hyperplasia should consider an alternative therapy as the efficacy of tadalafil 2.5mg for the treatment of benign prostatic hyperplasia has not been demonstrated.
Special populations: Elderly men: Dose adjustments are not required in elderly patients. Buy Cialis Online, tadalafil for sale in Australia
Men with renal impairment: Dose adjustments are not required in patients with mild to moderate renal impairment. For patients with severe renal impairment 10 mg is the maximum recommended dose for on-demand treatment.
5 mg: Once-a-day dosing of 2.5 or 5 mg tadalafil both for the treatment of erectile dysfunction or benign prostatic hyperplasia is not recommended in patients with severe renal impairment (see Precautions and Pharmacology: Pharmacokinetics under Actions).
20 mg: Once-a-day dosing of tadalafil is not recommended in patients with severe renal impairment (see Precautions and Pharmacology: Pharmacokinetics under Actions). Buy Cialis Online, tadalafil for sale in Australia
Men with hepatic impairment: For the treatment of erectile dysfunction using on-demand CIALIS the recommended dose of CIALIS is 10 mg taken prior to anticipated sexual activity and with or without food. There is limited clinical data on the safety of CIALIS in patients with severe hepatic impairment (Child-Pugh Class C); if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician. There are no available data about the administration of doses higher than 10 mg of tadalafil to patients with hepatic impairment.
Once-a-day dosing of CIALIS both for the treatment of erectile dysfunction and benign prostatic hyperplasia has not been evaluated in patients with hepatic impairment; therefore, if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician. (see Precautions and Pharmacology: Pharmacokinetics under Actions). Buy Cialis Online, tadalafil for sale in Australia
Men with diabetes: Dose adjustments are not required in diabetic patients.
Paediatric population: There is no relevant use of CIALIS in the paediatric population with regard to the treatment of erectile dysfunction.
Method of administration: CIALIS film-coated tablet if for oral use.
| Quantity | 100 Tablets, 200 Tablets, 500 Tablets |
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